Reviewed by the Cure.Care Medical Board · Updated June 2026
The Skin Care Encyclopedia

Understand your skin, clearly and calmly

Clear, dermatology-reviewed answers on common skin conditions, active ingredients, and everyday routines. Learn what triggers a flare-up, how your routine actually works, and when it is time to see a doctor, with no jargon and no product bias.

500+ Skin Conditions
250+ Ingredients
100+ Symptoms
Expert Reviewed
When to get urgent help: A fast-spreading rash, facial or throat swelling that affects breathing, or skin blistering with a high fever needs emergency care. Call your local emergency number or go to the nearest emergency department, do not wait.
Skin Conditions A–Z

What is your skin
trying to tell you?

Browse our medically-reviewed index of the most common skin conditions. Each entry explains causes, triggers, treatment pathways, and when to seek professional care.

480+ skin conditions indexed and medically reviewed in our full encyclopedia.

Browse conditions alphabetically or filter by body location, skin type, or trigger.

Browse Full A–Z Index
Evidence-Based Actives

Ingredients that are
clinically proven to work

150+ cosmetic actives decoded by our dermatology board — mechanism of action, evidence strength, safe concentration ranges, and what never to combine.

Evidence strength: Strong RCT Good clinical data Emerging
Most Researched Active Strong RCT Evidence

Retinol

Vitamin A · Tretinoin (Rx) · Retinaldehyde · Retinyl Palmitate

The most extensively studied cosmetic active in dermatology. Retinol binds to retinoic acid receptors, accelerating cell turnover, stimulating collagen synthesis, and normalising follicular keratinisation. Prescription tretinoin is retinoic acid directly — roughly 20× more potent than OTC retinol.

Works on
Fine lines · Acne · Uneven tone · Texture · Pores
Start with
0.025–0.05% retinol · 2–3× per week · PM only
Avoid with
Benzoyl peroxide · AHAs/BHAs same night · Vitamin C

Avoid during pregnancy. Retinoids are teratogenic. Consult a doctor before use. Not recommended while breastfeeding.

Full Retinol Deep Dive

Retinoid Potency Spectrum

  1. Retinyl Palmitate
    Mildest
  2. Retinol (OTC)
    Mild
  3. Retinaldehyde
    Moderate
  4. Adapalene 0.1%
    Moderate+
  5. Tretinoin (Rx only)
    Strongest

Higher potency = more effective and more irritation risk. Always start at the lowest strength.

Don't use these combinations on the same application
  • Retinol + Vitamin C Both are pH-sensitive — competing environments reduce efficacy of both
  • Retinol + BHA / AHA Compounding irritation risk — use on alternate nights instead
  • Benzoyl Peroxide + Retinol BPO oxidises and degrades retinol molecules, rendering it ineffective
  • Vitamin C + Niacinamide May reduce efficacy of both at high concentrations — use AM / PM separately
Full compatibility matrix

150+ active ingredients decoded with full evidence ratings, usage guides and safe-combination maps.

Each entry reviewed by our dermatology board and updated quarterly with published research.

Browse All Ingredients
Build Your Routine

The right order to
layer your skincare

Apply products from thinnest to thickest texture. Cleanse, treat, moisturise, then protect in the morning. Getting the order right is what lets each active actually absorb and work.

  1. Gentle cleanser

    A mild morning wash removes overnight oil without stripping the barrier. A water rinse alone is fine for dry or sensitive skin.

    Cleanser guide
  2. Antioxidant serum

    Vitamin C in the morning helps defend against daytime free-radical damage and supports an even tone. Apply to clean, dry skin.

    Vitamin C guide
  3. Moisturiser

    Lock in hydration and support the skin barrier. Lightweight gels suit oily skin; richer creams suit dry skin.

    Moisturiser guide
  4. Broad-spectrum SPFMost important step

    Daily sunscreen (SPF 30+) is the single most effective anti-ageing and pigmentation-prevention step. The American Academy of Dermatology reports that up to 90% of visible skin ageing is linked to sun exposure.1

    Sunscreen guide

Patch test first, and start slow. Introduce one active at a time and stop if you develop persistent burning, swelling or a spreading rash. If you are pregnant, breastfeeding, or managing a skin condition, ask a doctor or dermatologist before starting actives such as retinoids.

Sources & References

  1. American Academy of Dermatology Association. "How to maintain your skin's health." aad.org, 2024. aad.org
  2. World Health Organization. "Ultraviolet radiation and skin health." who.int, 2023. who.int
  3. NHS. "Sunscreen and sun safety." nhs.uk, 2023. nhs.uk
Know Your Skin

Find your
skin type

Wash your face, wait an hour without products, then notice how it feels. That simple test tells you which of the five skin types you have, and which routine will actually suit you.

The 60-minute bare-skin test

Cleanse with a gentle wash, pat dry, and apply nothing for one hour. How your skin feels after that hour is the clearest signal of your natural skin type.

Your skin type can change. Age, hormones, climate and products all shift how your skin behaves, so reassess seasonally. Persistent redness, itching or breakouts that do not settle are worth discussing with a dermatologist rather than self-treating.

Know When to Get Help

When to see a
dermatologist

Most everyday skin concerns settle with gentle, consistent care. But some signs mean it is time for professional help, and a few need urgent attention. Here is how to tell the difference.

Usually fine to manage at home

With gentle, consistent care

  • Occasional mild breakouts that clear on their own
  • General dryness, dullness or mild flaking
  • Mild uneven tone or early texture concerns
  • Mild stinging when starting a new active, that settles

Book a dermatologist

Worth a professional opinion

  • Breakouts that do not improve after a few weeks of care
  • Painful, deep or cystic acne, or breakouts that scar
  • Persistent redness, itching or rashes that keep returning
  • A mole or spot that changes in size, shape or colour1
Seek urgent medical care now

Some skin signs can point to a serious reaction or infection. Do not wait for an appointment if you notice any of the following:

  • A rash that spreads quickly across the body
  • Swelling of the face, lips or throat, or any difficulty breathing
  • Skin blistering or peeling alongside a high fever
  • A skin wound that is hot, rapidly worsening, or streaking outward

Call your local emergency number or go to the nearest emergency department.

Ready to talk to a professional?

A dermatologist can diagnose accurately and prescribe treatments that are not available over the counter.

Sources & References

  1. American Academy of Dermatology Association. "What to look for: ABCDEs of melanoma." aad.org, 2024. aad.org
  2. NHS. "When to get medical help for skin symptoms." nhs.uk, 2023. nhs.uk
  3. World Health Organization. "Skin conditions and access to care." who.int, 2023. who.int
Skincare Questions

Your skincare
questions, answered

Clear, dermatology-reviewed answers to the questions people ask most. Tap any question to read the full answer.

  • Apply from thinnest to thickest texture. A simple, reliable order is: cleanser, then a water-based treatment serum, then moisturiser, and in the morning finish with broad-spectrum SPF 30 or higher.

    See the full routine guide
  • Most active ingredients need around 8 to 12 weeks of consistent use before visible results, reflecting the skin's natural renewal cycle. Hydration can feel better within days, but tone and texture changes take longer. Consistency matters more than adding extra products.

    Explore active ingredients
  • It is usually easier to separate them: vitamin C in the morning, retinol at night. This reduces the chance of irritation and lets each ingredient work in its preferred conditions. Introduce only one new active at a time.

    Read the retinol guide
  • If you sit near windows or daylight, daily sunscreen still helps because UVA passes through glass. For most people, applying SPF every morning is the simplest reliable habit, indoors or out.

    Sunscreen guide
  • Some actives that speed cell turnover, such as retinoids, can cause a temporary increase in breakouts in the first few weeks. However, persistent irritation, swelling or a spreading rash is not purging, and should prompt you to stop and seek advice from a dermatologist.

    Find a dermatologist

Have a different question?

Browse all skin health answers

Sources & References

  1. American Academy of Dermatology Association. "Skin care tips and how products work." aad.org, 2024. aad.org
  2. NHS. "Sunscreen and sun safety." nhs.uk, 2023. nhs.uk
  3. World Health Organization. "Radiation: Ultraviolet (UV) radiation." who.int, 2023. who.int
Our Products

Skincare from a brand that
teaches first

The same evidence-led thinking behind our guides goes into the Cure.Care skin range: simple, considered formulations with full ingredient transparency and no inflated promises.

Browse the range

Cure.Care branded products are cosmetic skincare, not medicines, and are not intended to diagnose, treat or cure any condition. Full ingredient and manufacturer details are shown on each product page.

Our Standards

Skincare you can
actually trust

Skin advice is everywhere, and most of it is selling something. Every page on Cure.Care is written for clarity, reviewed for accuracy, and grounded in evidence, with no product bias.

  • Medically reviewed

    Skincare content is checked by qualified healthcare professionals on the Cure.Care Medical Board before it is published.

  • Evidence-based

    Guidance is grounded in dermatology research and authorities such as the AAD, NHS and WHO, not trends or marketing claims.

  • Kept current

    Pages are revisited and updated as new dermatological guidelines and research emerge, with visible review dates.

  • No product bias

    We explain how ingredients and routines work, not which brand to buy. Educational value always comes before commerce.

Reviewed by the Cure.Care Medical Board

An editorial board of qualified healthcare professionals · Skin content last reviewed June 2026

Cure.Care provides educational information about skin health and is not a substitute for professional medical advice, diagnosis or treatment. Always consult a qualified healthcare professional about your individual skin concerns.